Институт теоретической физики им. Л.Д. Ландау

Российской академии наук

Семинары на ученом совете ИТФ им. Л.Д. Ландау

Eukaryotic cell polarity and protein sorting

27 апреля в 11:30

Andrea Gamba, Politecnico di Torino

I will review some of the biophysical processes that allow eukaryotic cells to break their native symmetry and polarize in order to provide adequate responses to signals and properly adapt to the environment. An essential part of the process is the incessant spatial reorganization of membrane-bound proteins due to the action of reinforcing biochemical feedback loops that contrast the homogenizing effect of diffusion. A second component is the coupling of protein and lipid dynamics: protein crowding induces the bending of lipid membranes and the nucleation of small lipid vesicles enriched in specific molecular factors destined to be targeted to appropriate destinations. This mechanism leads to an incessant distillation process controlled by the strength of protein-protein interactions. A phenomenological theory of the process can be developed, predicting the existence of an optimal distillation regime characterized by simple scaling laws. Experiments suggest that living cells work close to this optimal regime, likely as the result of evolutionary pressure.

Dielectric response of Anderson and pseudogapped insulators

27 апреля в 11:30

M.V. Feigel'man, D.A. Ivanov, E. Cuevas

Using a combination of analytic and numerical methods, we study the polarizability of a (non-interacting) Anderson insulator in one, two, and three dimensions and demonstrate that, in a wide range of parameters, it scales proportionally to the square of the localization length, contrary to earlier claims based on the effective-medium approximation. We further analyze the effect of electron-electron interactions on the dielectric constant in quasi-1D, quasi-2D and 3D materials with large localization length, including both Coulomb repulsion and phonon-mediated attraction. The phonon-mediated attraction (in the pseudogapped state on the insulating side of the Superconductor-Insulator Transition) produces a correction to the dielectric constant, which may be detected from a linear response of a dielectric constant to an external magnetic field.

TBA (приглашенный доклад)

22 июня в 11:30

Леонид Глазман

Семинары проходят по пятницам в конференц-зале Института теоретической физики им. Л.Д. Ландау, начало в 11:30. Адрес: Черноголовка, МО, просп. Академика Семенова, д. 1-A

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